Acutely, it can be dosed in pill form at the same dosage or given intravenously as magnesium sulfate at 1-2 gm. Magnesium oxide is frequently used in pill form to prevent migraine, usually at a dose of 400-600 mg per day. Of course, no such medication exists, but magnesium comes closer than many interventions on all these fronts. Magnesium can interfere with how well this drug is absorbed, so the supplement should be taken at least two hours before or after these medications.The ideal medication for prevention and treatment of migraine would have no side effects, no risk, would be safe in pregnancy, as well as be highly effective while remaining inexpensive.
Another group of drugs that magnesium tends to interact with is bisphosphonates that are often used to treat osteoporosis. It is usually recommended to take antibiotics at least 2 hours before or 4 to 6 hours after a magnesium-containing supplements.
Magnesium can also interact with certain medications, for example, with certain types of antibiotics. As a general rule, you should always talk to your doctor before taking a new supplement. Fatal hypermagnesemia can occur in those with renal problems when taking these laxatives because kidneys that are not fully functional are not able to effectively clear magnesium from the body. Keep in mind that an overdose of this measure would require a person to take thousands of milligrams of magnesium daily, which is well beyond the dose in a typical magnesium supplement.Īlthough it would be difficult to overdose on magnesium-rich foods or magnesium supplements, magnesium is also the primary ingredient in some prescription and over-the-counter laxatives, and severe hypermagnesemia has been reported to occur from taking laxatives that contain magnesium for constipation over a long-term period. Overdosing on magnesium can cause serious side effects, including an irregular heartbeat, low blood pressure, confusion, slowed breathing, coma, and even a few deaths have been reported. Hypermagnesemia is the name for a magnesium overdose, which is rare but more common in individuals with kidney disease because the kidneys are responsible for excreting excess magnesium and work to regulate magnesium balance in the body. Magnesium citrate and magnesium glycinate are more bioavailable than other common forms of magnesium like magnesium oxide.* They are both great options for magnesium supplementation, depending on your specific needs, whether they be correcting a deficiency and helping with sleep and relaxation (in which case go with the glycinate form), or increasing gut motility and supporting digestion (for these go with the citrate form).* Brighten, "Magnesium glycinate is highly absorbable, doesn't cause diarrhea like the citrate form can, and has a calming effect."* Magnesium citrate has a laxative effect, but in many cases that's actually a benefit since it's used specifically to treat constipation due to its ability to increase gut motility.* Of all the forms of magnesium, magnesium glycinate is least likely to cause diarrhea, and experts also turn to it for the treatment of a magnesium deficiency due to its high absorbency rate.* According to Dr. Magnesium citrate is one of the other most commonly recommended sources of magnesium.